Hodinový prehľad - Zdravotnícke a vedecké zaujímavosti

Súhrn: Higher lithium levels in drinking water were associated with an increased odds of Wolff-Parkinson-White (WPW) syndrome diagnosis among children, according to new research “These data suggest that the development of these accessory pathways, responsible for clinically relevant arrhythmias and, at times, risks for sudden death, may have an identifiable and modifiable cause,” said Gregory Marcus, MD, MAS, study investigator and endowed professor in atrial fibrillation research at the University of California, San Francisco “We therefore hope this might open up future research into the prevention of these accessory pathways from occurring in the first place.

Súhrn: The Medicines and Healthcare products Regulatory Agency (MHRA) has authorised plozasiran (Redemplo, Arrowhead Pharmaceuticals) to reduce triglyceride levels in adults with the rare recessive genetic disorder familial chylomicronaemia syndrome (FCS), alongside a low-fat diet Julian Beach, the MHRA’s executive director of operations, said in a press release that the authorisation provides an additional treatment option for adults with FCS, a condition that can cause serious and painful complications The active treatment group had a median reduction in triglyceride levels of around 80% at 10 months, compared with 17% among those receiving placebo.

Súhrn: TOPLINE A 16-fraction radiotherapy regimen achieved locoregional control comparable to conventional 25-fraction radiotherapy in patients with high-risk breast cancer requiring internal mammary node irradiation (IMNI), with 5-year locoregional recurrence rates of 1 To investigate, researchers conducted a phase 3 noninferiority trial, enrolling 1494 women with high-risk disease (pathologic stage T1-4N2-3, T3-4N1, or T1-2N1 with additional high-risk factors) after mastectomy with negative margins and axillary lymph node dissection - Participants were randomly assigned 1:1 to receive either hypofractionated radiotherapy (HypoRT; 42.