Hodinový prehľad - Zdravotnícke a vedecké zaujímavosti

Súhrn: Skin-Only LCH Is Usually Treatment Responsive With skin-only disease, healing is typically achieved with minimal sequelae — such as minor scarring or dyspigmentation — but the risk for recurrence, most often occurring in the organ previously affected, still approaches 20% Despite the fact that LCH is rare, Koh called for a high index of suspicion, not least because early treatment offers better outcomes He advised, however, that all therapy be stopped 2 weeks before the biopsy to provide a better specimen.

Súhrn: Endoscopic scores also improved significantly, and health-related quality of life (HRQOL) increased, though a numeric rise in endoscopic suspicion of candidiasis was observed METHODOLOGY - Researchers conducted a retrospective analysis of a prospectively collected dataset including 45 adult patients with EoE who switched from BVS to BOT at the same dose (1 mg) and dosing schedule (32 patients switched in a once-daily [OD] schedule; 13 in a twice-daily schedule) at University Hospitals Leuven, Belgium - Patients had been on BVS therapy for a median of 440 days (OD group) or 112 days (twice-daily group) before switching to BOT.

Súhrn: The investigational gene therapy ixoberogene soroparvovec (Ixo-vec) helped patients maintain vision and left active levels of the therapeutic protein in the eye 5 years after an initial injection, according to results of an extension trial presented at the American Society of Retina Specialists (ASRS) 2026 Annual Meeting in Montreal The drug, a long-term treatment for neovascular age-related macular degeneration (AMD), also significantly reduced the need for supplemental injections “For a first-in-human program in a chronic, vision-threatening disease, the 5-year data are extremely encouraging,” said Szilard Kiss, MD, professor of ophthalmology and genetic medicine at Weill Cornell Medicine in New York City.