Vygenerované: 30.01.2026 16:21:19
Súhrn: - Home - Medical news & Guidelines - Anesthesiology - Cardiology and CTVS - Critical Care - Dentistry - Dermatology - Diabetes and Endocrinology - ENT - Gastroenterology - Medicine - Nephrology - Neurology - Obstretics-Gynaecology - Oncology - Ophthalmology - Orthopaedics - Pediatrics-Neonatology - Psychiatry - Pulmonology - Radiology - Surgery - Urology - Laboratory Medicine - Diet - Nursing - Paramedical - Physiotherapy - Health news - Fact Check - Bone Health Fact Check - Brain Health Fact Check - Cancer Related Fact Check - Child Care Fact Check - Dental and oral health fact check - Diabetes and metabolic health fact check - Diet and Nutrition Fact Check - Eye and ENT Care Fact Check - Fitness fact check - Gut health fact check - Heart health fact check - Kidney health fact check - Medical education fact check - Men's health fact check - Respiratory fact check - Skin and hair care fact check - Vaccine and Immunization fact check - Women's health fact check - AYUSH - State News - Andaman and Nicobar Islands - Andhra Pradesh - Arunachal Pradesh - Assam - Bihar - Chandigarh - Chattisgarh - Dadra and Nagar Haveli - Daman and Diu - Delhi - Goa - Gujarat - Haryana - Himachal Pradesh - Jammu & Kashmir - Jharkhand - Karnataka - Kerala - Ladakh - Lakshadweep - Madhya Pradesh - Maharashtra - Manipur - Meghalaya - Mizoram - Nagaland - Odisha - Puducherry - Punjab - Rajasthan - Sikkim - Tamil Nadu - Telangana - Tripura - Uttar Pradesh - Uttrakhand - West Bengal - Medical Education - Industry Solriamfetol Reduces Excessive Sleepiness in Early-Morning Shift Work Disorder: New Trial Shows USA: A new randomized clinical trial published in NEJM Evidence suggests that solriamfetol may significantly reduce excessive sleepiness in people working early-morning shifts, a population that has received far less research attention than night-shift workers, despite being more common The findings offer promising evidence for a targeted treatment option for early-morning shift work disorder (SWD) - After four weeks of treatment, participants receiving solriamfetol showed significantly better objective wakefulness compared with those given placebo.
Doplnenie: - Solriamfetol-treated patients demonstrated an average increase of 9.
Súhrn: - Home - Medical news & Guidelines - Anesthesiology - Cardiology and CTVS - Critical Care - Dentistry - Dermatology - Diabetes and Endocrinology - ENT - Gastroenterology - Medicine - Nephrology - Neurology - Obstretics-Gynaecology - Oncology - Ophthalmology - Orthopaedics - Pediatrics-Neonatology - Psychiatry - Pulmonology - Radiology - Surgery - Urology - Laboratory Medicine - Diet - Nursing - Paramedical - Physiotherapy - Health news - Fact Check - Bone Health Fact Check - Brain Health Fact Check - Cancer Related Fact Check - Child Care Fact Check - Dental and oral health fact check - Diabetes and metabolic health fact check - Diet and Nutrition Fact Check - Eye and ENT Care Fact Check - Fitness fact check - Gut health fact check - Heart health fact check - Kidney health fact check - Medical education fact check - Men's health fact check - Respiratory fact check - Skin and hair care fact check - Vaccine and Immunization fact check - Women's health fact check - AYUSH - State News - Andaman and Nicobar Islands - Andhra Pradesh - Arunachal Pradesh - Assam - Bihar - Chandigarh - Chattisgarh - Dadra and Nagar Haveli - Daman and Diu - Delhi - Goa - Gujarat - Haryana - Himachal Pradesh - Jammu & Kashmir - Jharkhand - Karnataka - Kerala - Ladakh - Lakshadweep - Madhya Pradesh - Maharashtra - Manipur - Meghalaya - Mizoram - Nagaland - Odisha - Puducherry - Punjab - Rajasthan - Sikkim - Tamil Nadu - Telangana - Tripura - Uttar Pradesh - Uttrakhand - West Bengal - Medical Education - Industry Markedly high prevalence of vitamin D deficiency in older patients presenting with hip fractures: study Hip fractures are the most common low‑energy injury affecting older adults and place a large burden on healthcare systems Vitamin D sufficiency is fundamental to healthy bone turnover, maintenance of muscular strength, and immune system homeostasis Mousa C et al conducted a study to evaluate the prevalence of vitamin D deficiency among patients admitted with recent fragility hip fractures at a single orthopedic clinic over one year.
Doplnenie: This retrospective study included patients aged >50 years admitted to the General Hospital of Athens “KAT” with fragility hip fractures during 12 months.
Súhrn: Researchers discover genetic ancestry is a critical component of assessing head and neck cancerous tumors Sadie Harley scientific editor Andrew Zinin lead editor Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC) Analyzing data from 523 patients stored in The Cancer Genome Atlas (TCGA)—the largest biological database for several cancer types—the study, published in Cancer and Metastasis Reviews, identified the important role of genetic differences in association with gene mutations or changes that drive how quickly tumor cells divide and whether they will respond to chemotherapy or spread to other organs The researchers found that ancestry, rather than self-identified race, was a stronger predictor of genetic differences between the tumors.
Doplnenie: African-American patients survive on average two and a half years after being diagnosed with head and neck squamous cell carcinoma (HNSCC), the technical name for head and neck cancer.
Súhrn: Media alert A CDC food safety alert linked to moringa leaf powder has been updated: https://www gov/salmonella/outbreaks/supergreenssupplementpowders-1-26/index html Key Points: - As of January 29, 2026, total of 65 people in 28 states have now been reported as part of this outbreak.
Doplnenie: An additional strain of Salmonella is now included in the investigation.
Súhrn: - Home - Medical news & Guidelines - Anesthesiology - Cardiology and CTVS - Critical Care - Dentistry - Dermatology - Diabetes and Endocrinology - ENT - Gastroenterology - Medicine - Nephrology - Neurology - Obstretics-Gynaecology - Oncology - Ophthalmology - Orthopaedics - Pediatrics-Neonatology - Psychiatry - Pulmonology - Radiology - Surgery - Urology - Laboratory Medicine - Diet - Nursing - Paramedical - Physiotherapy - Health news - Fact Check - Bone Health Fact Check - Brain Health Fact Check - Cancer Related Fact Check - Child Care Fact Check - Dental and oral health fact check - Diabetes and metabolic health fact check - Diet and Nutrition Fact Check - Eye and ENT Care Fact Check - Fitness fact check - Gut health fact check - Heart health fact check - Kidney health fact check - Medical education fact check - Men's health fact check - Respiratory fact check - Skin and hair care fact check - Vaccine and Immunization fact check - Women's health fact check - AYUSH - State News - Andaman and Nicobar Islands - Andhra Pradesh - Arunachal Pradesh - Assam - Bihar - Chandigarh - Chattisgarh - Dadra and Nagar Haveli - Daman and Diu - Delhi - Goa - Gujarat - Haryana - Himachal Pradesh - Jammu & Kashmir - Jharkhand - Karnataka - Kerala - Ladakh - Lakshadweep - Madhya Pradesh - Maharashtra - Manipur - Meghalaya - Mizoram - Nagaland - Odisha - Puducherry - Punjab - Rajasthan - Sikkim - Tamil Nadu - Telangana - Tripura - Uttar Pradesh - Uttrakhand - West Bengal - Medical Education - Industry Paricalcitol vs Calcitriol: Paricalcitol linked to stronger and faster PTH Control, reveals study Researchers have found in a new study that Paricalcitol produces a stronger and faster reduction in parathyroid hormone levels compared with calcitriol, making it preferable in patients with very high PTH For these patients, the "Kidney Disease: Improving Global Outcomes" clinical practice guidelines recommend PTH levels be maintained in the range of two to nine times of the upper normal limit Both agents are effective in maintaining PTH within target ranges, with calcitriol offering a slower and more limited decline.
Doplnenie: Parathyroid hormone (PTH) levels may fluctuate in patients undergoing hemodialysis because of changes in calcium, phosphorus, and vitamin D levels.
Súhrn: - Home - Medical news & Guidelines - Anesthesiology - Cardiology and CTVS - Critical Care - Dentistry - Dermatology - Diabetes and Endocrinology - ENT - Gastroenterology - Medicine - Nephrology - Neurology - Obstretics-Gynaecology - Oncology - Ophthalmology - Orthopaedics - Pediatrics-Neonatology - Psychiatry - Pulmonology - Radiology - Surgery - Urology - Laboratory Medicine - Diet - Nursing - Paramedical - Physiotherapy - Health news - Fact Check - Bone Health Fact Check - Brain Health Fact Check - Cancer Related Fact Check - Child Care Fact Check - Dental and oral health fact check - Diabetes and metabolic health fact check - Diet and Nutrition Fact Check - Eye and ENT Care Fact Check - Fitness fact check - Gut health fact check - Heart health fact check - Kidney health fact check - Medical education fact check - Men's health fact check - Respiratory fact check - Skin and hair care fact check - Vaccine and Immunization fact check - Women's health fact check - AYUSH - State News - Andaman and Nicobar Islands - Andhra Pradesh - Arunachal Pradesh - Assam - Bihar - Chandigarh - Chattisgarh - Dadra and Nagar Haveli - Daman and Diu - Delhi - Goa - Gujarat - Haryana - Himachal Pradesh - Jammu & Kashmir - Jharkhand - Karnataka - Kerala - Ladakh - Lakshadweep - Madhya Pradesh - Maharashtra - Manipur - Meghalaya - Mizoram - Nagaland - Odisha - Puducherry - Punjab - Rajasthan - Sikkim - Tamil Nadu - Telangana - Tripura - Uttar Pradesh - Uttrakhand - West Bengal - Medical Education - Industry Bristol Myers Approaches SC to Halt Zydus' Biosimilar Nivolumab Sale New Delhi: Bristol Myers Squibb has approached the Supreme Court of India, seeking to restrain Zydus Lifesciences from manufacturing and selling its biosimilar version of the cancer drug nivolumab, escalating the legal battle over patent rights and market exclusivity in the Indian oncology drug space In its plea before the apex court, Bristol Myers Squibb has argued that Zydus’s biosimilar infringes upon its intellectual property related to nivolumab, a monoclonal antibody used extensively in the treatment of multiple cancers The company has positioned its product as a lower-cost alternative aimed at improving patient access to life-saving oncology treatments.
Doplnenie: The legal challenge follows an earlier decision by the Delhi High Court, which allowed Zydus to proceed with the sale of its biosimilar nivolumab product.
Súhrn: Dobré ránko! Leto sa nám pomaly končí, ale nesmúť, je tu nový Imuno MD Čo ťa dnes čaká? Pozrieme sa na varovné príznaky vrodených porúch imunity a na možnosti kombinácie alergénovej imunoterapie a biologickej liečby v manažmente inhalačnej alergie Počul*a si už o syndróme VEXAS? V dnešnom imunokvíze si overíme, čo o ňom vieš.
Doplnenie: 😁 S prípravou dnešného newslettra mi pomohla Otília Petrovičová.
Súhrn: Overview At its December 2025 meeting, the Centers for Disease Control and Prevent (CDC) Advisory Committee on Immunization Practices (ACIP) voted to recommend individual-based decision-making for infants born to mothers who test negative for hepatitis B Key points CDC now recommends shared decision-making for hepatitis B birth doses when mothers test negative Infants born to mothers who test positive for hepatitis B or whose status is unknown should still receive the vaccine within 12 hours of birth.
Doplnenie: The CDC adopted this recommendation on December 16, 2025.
Súhrn: TRNAVA: Polícia vyšetruje okolnosti dopravnej nehody, pri ktorej 15 januára ráno zachytilo osobné auto chodkyňu na priechode pre chodcov v trnavskej mestskej časti Modranka Mladá žena musela byť prevezená na ošetrenie do trnavskej nemocnice.
Doplnenie: Trnavská krajská polícia o tom informovala na sociálnej sieti.
Súhrn: Media alert A new CDC food safety alert regarding a multistate outbreak of Salmonella infections has been posted at https://www gov/salmonella/outbreaks/supergreenssupplementpowders-1-26/index Key Points: - 45 people across 21 states have gotten sick with the same strain of Salmonella.
Doplnenie: 12 people have been hospitalized, and no deaths have been reported.
Súhrn: — JANUARY 5, 2026 — Deputy Secretary of Health and Human Services Jim O'Neill, in his role as Acting Director of the Centers for Disease Control and Prevention (CDC), today signed a decision memorandum* accepting recommendations from a comprehensive scientific assessment of U After consulting with health ministries of peer nations, considering the assessment's findings, and reviewing the decision memo presented by National Institutes of Health Director Dr Release WASHINGTON, D.
Doplnenie: On December 5, 2025, via a Presidential Memorandum, President Trump directed the Secretary of HHS and the Acting Director of CDC to examine how peer, developed nations structure their childhood vaccination schedules and to evaluate the scientific evidence underlying those practices.
Súhrn: Winter changes more than the weather—it changes how we connect How to stay socially engaged Sadie Harley scientific editor Andrew Zinin lead editor Throughout Earth's history, life in temperate and polar zones has had to contend with the cold and darkness of winter Across species, seasonal adaptation is the norm.
Doplnenie: Some animals hibernate, others migrate, and many reduce activity, conserve energy, and narrow their social and ecological range until conditions improve.
Súhrn: 'I get nightmares': Child tells BBC of botched surgery by disgraced GOSH surgeon A former patient of Yaser Jabbar has spoken to the BBC about his experience with the limb reconstruction surgeon when he was just six years old "We saw some mistakes on my leg and we realised something happened wrong", 12-year-old Vivaan Sharma said An investigation, published by London's Great Ormond Street Hospital (GOSH) into Jabbar, found widespread evidence of unacceptable practice in the botched operations he carried out.
Doplnenie: Jabbar worked at the hospital between 2017 and 2022, providing care to 789 children – 94 of them came to harm, GOSH's report concluded.
Súhrn: Prezident SR Peter Pellegrini vyzval na zlepšenie pracovných podmienok záchranných a bezpečnostných zložiek štátu Zároveň si želá, aby sa zbory nestávali predmetom politického súperenia Hlava štátu to uviedla počas príhovoru pri piatkovom prijatí zástupcov záchranných a bezpečnostných zborov.
Doplnenie: Prezidentka Policajného zboru Jana Maškarová sa poďakovala rodinám záchranárov, hasičov a policajtov za ich podporu, pochopenie a trpezlivosť.
Súhrn: Bližšie sa pozrieme práve na nich: 🔄 U všetkých pacientov bola indikovaná substitúcia imunoglobulínov (IgRT, immunoglobulin replacement therapy ), vďaka čomu ani jeden z nich neprekonal infekciu so závažným priebehom Ahoj! Keďže vonku sa nám značne ochladilo, zahrejeme sa témou z oblasti Stredozemného mora Tušíš správne, bude to o autoinflamácii.
Doplnenie: V dnešnom Imuno MD: 🧬 Nový pohľad na IGLL1 deficit 📝 Imuno kvíz 🔥 Familiárna stredomorská horúčka v praxi Užívaj! Aktuálna imuno štúdia v skratke 🧬 Nečakane vysoká incidencia zriedkavej poruchy imunity Nedávno sme si posvietili na skríning vrodených porúch imunity.
Súhrn: Proteomika je vědní obor studující proteom – soubor všech proteinů v buňce, tkáni nebo celém organismu Proteom je vysoce proměnlivý v čase i prostoru a jeho analýzy vyžadují specifické přístupy a využití pokročilých technologií Obsahem článku je stručný úvod do proteomiky a popis základních proteomických metod založených na protilátkách a hmotnostní spektrometrii.
Doplnenie: Navazující článek Hmotnostní spektrometrie – co to je a k čemu je to dobré? (Živa 2025, 6) K dalšímu čtení v Živě Proteinová sekrece buněk savců aneb jak si buňky povídají a jak jim naslouchat (2013, 2) Ze života bílkovin aneb Na tvaru záleží (2020, 6) Biochemické metody využívané v lékařství 1.
Súhrn: Prosecutors have alleged Halifax-based RT Diagnostics "purported to be a testing laboratory" when in reality tests were "dumped in a room" with customers sent fake negative results for the deadly virus, thereby endangering people's health Medical safety inspectors previously told the trial the firm's laboratory at Park Works "looked like a building site", with the number of positive tests it returned also described as "suspiciously low" 'We weren't perfect', says bogus Covid lab accused An ex-politician accused of running a bogus coronavirus testing firm has told a court he "never said we were absolutely bob-on" in its operation.
Doplnenie: Mr Shoukat, a pharmacist from Halifax, and Mr Malik, from Burnley, are also accused of money laundering.