Vygenerované: 14.12.2025 19:40:51
Súhrn: By 2024, both the number of cases and the notification rate reached the highest levels since 2007,” Áine Collins, PhD, expert in foodborne, vector-borne, and zoonotic diseases at the European Centre for Disease Prevention and Control (ECDC), told Medscape News Europe It is considered one of the most serious foodborne diseases under EU surveillance because of its high rates of hospitalization and substantial morbidity and mortality Listeria caused the highest proportion of hospitalizations and deaths of any foodborne illness across the EU in 2024, according to a new report by the European Food Safety Authority (EFSA).
Doplnenie: Case numbers have risen significantly since 2020.
Súhrn: Hypertrophic cardiomyopathy is the most common form of genetic cardiovascular disease and the most common cause of sudden death in young people The European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for Myqorzo (aficamten, Cytokinetics) for treating adults with obstructive hypertrophic cardiomyopathy (oHCM) It is caused by mutations in genes encoding the cardiac sarcomere protein.
Doplnenie: oHCM happens when thickened heart muscle and abnormal motion of the mitral valve block blood flow from the left ventricle.
Súhrn: According to a recent Organization for Economic Co-operation and Development report, patients who believe that their primary care clinician has spent sufficient time with them are nearly 90% more likely to trust their healthcare system A simulation study published in Applied Clinical Informatics evaluated an increase in the average consultation time from 5 to 10 minutes This finding highlights a fundamental crisis in modern practice: Time is the basis of trust.
Doplnenie: The struggle to secure even a 10-minute consultation is a defining challenge for primary care, exacerbated by unrelenting demand and structural physician shortages.
Súhrn: TOPLINE: In patients with inflammatory bowel disease (IBD), a response to the first advanced therapy lasting 12 months or more was associated with a reduced risk for hospitalisation due to surgery or rescue treatment; responders experienced a significantly longer time to hospitalisation than non-responders METHODOLOGY: - Researchers conducted a retrospective cross-sectional analysis using a national database to assess the link between treatment response to the first biologic exposure and long-term surgery and hospitalisation outcomes in the UK population - They analysed data of 15,531 adults recruited from hospitals (January 2017 to October 2023), including 10,024 patients with Crohn's disease and 5507 patients with ulcerative colitis (UC).
Doplnenie: - These patients received at least one advanced therapy, including infliximab, adalimumab, golimumab, ustekinumab, vedolizumab, risankizumab, mirikizumab, tofacitinib, upadacitinib, filgotinib, ozanimod, and etrasimod.
Súhrn: But new research suggests SO may contribute to weight gain and postulates a potential mechanism behind this effect Although the study was conducted in mice, the researchers said it could have implications for humans But the quantities in which we consume it are triggering pathways our bodies didn’t evolve to handle,” senior author Frances Sladek, PhD, professor of cell biology and toxicologist, Department of Cell, Molecular, and Systems Biology, University of California Riverside, told Medscape Medical News.
Doplnenie: “Soybean oil isn’t toxic per se.